Medical Interests A wide spectrum of neurological problems and conditions including but not limited to migraines, headaches, non-surgical neck and back pain (acute and chronic), gait imbalance, insomnia with daytime fatigue, ADD, Alzheimer's, multiple sclerosis and nerve damage. He DID clearly explain why his decision to opt for surgery was the best choice. Long-term outcomes after carotid stent placement for treatment of carotid artery dissection, Gene therapy using viral vectors for acute neurologic insults, Planned direct dual-modality treatment of complex broad-necked intracranial aneurysms: Four technical case reports, Microsurgical resection of brainstem, thalamic, and basal ganglia angiographically occult vascular malformations, Neurosurgical and neuroendovascular management of Takayasu's arteritis, Rewarming from hypothermia leads to elevated plasma lipopolysaccharide concentrations, Institutional peer review can reduce the risk and cost of carotid endarterectomy, Diffusion- and perfusion-weighted magnetic resonance imaging of focal cerebral ischemia and cortical spreading depression under conditions of mild hypothermia, Delayed induction and long-term effects of mild hypothermia in a focal model of transient cerebral ischemia: neurological outcome and infarct size, Calbindin D28K overexpression protects striatal neurons from transient focal cerebral ischemia, Quantification of the gravity-dependent change in the C-arm image center for image compensation in fluoroscopic spinal neuronavigation, Posterior cerebral circulation revascularization, Differential neuroprotection from human heat shock protein 70 overexpression in in vitro and in vivo models of ischemia and ischemia-like conditions, Gene therapy for treatment of cerebral ischemia using defective herpes simplex viral vectors, Imaging of cerebral and brain stem amyloidomas, Hyperperfusion syndrome with hemorrhage after angioplasty for middle cerebral artery stenosis, Familial trigeminal neuralgia - Case report and review of the literature, Mild hypothermia increases Bcl-2 protein expression following global cerebral ischemia, Overexpression of HSP72 after induction of experimental stroke protects neurons from ischemic damage, Mild hypothermia reduces apoptosis of mouse neurons in vitro early in the cascade, Mild hypothermia attenuates cytochrome C release but does not alter Bcl-2 expression or caspase activation after experimental stroke, Safety and performance of a novel intravascular catheter for induction and reversal of hypothermia in a porcine model, Gene transfer of HSP72 protects cornu ammonis 1 region of the hippocampus neurons from global ischemia: Influence of Bcl-2, Effects of mild hypothermia on superoxide anion production, superoxide dismutase expression, and activity following transient focal cerebral ischemia, Early carotid endarterectomy after ischemic stroke improves diffusion/perfusion mismatch on magnetic resonance imaging: Report of two cases, Deep arteriovenous malformations of the basal ganglia and thalamus: natural history, Aneurysmal subarachnoid hemorrhage in patient's with Hunt and Hess grade 4 or 5: Treatment using the Guglielmi detachable coil system, Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity, Parent vessel occlusion for vertebrobasilar fusiform and dissecting aneurysms, Attenuation of nitric oxide synthase isoform expression by mild hypothermia after focal cerebral ischemia: variations depending on timing of cooling, Multimodality treatment of giant intracranial arteriovenous malformations, Gene therapy and hypothermia for stroke treatment, Mutational analysis of 206 families with cavernous malformations, Neurophysiological monitoring in the endovascular therapy of aneurysms, Glutathione peroxidase overexpression inhibits cytochrome c release and proapoptotic mediators to protect neurons from experimental stroke, Cellular and molecular events underlying ischemia-induced neuronal apoptosis, Mild postischemic hypothermia prolongs the time window for gene therapy by inhibiting cytochrome C release, Catalase over-expression protects striatal neurons from transient focal cerebral ischemia.

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