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Depending on circumstances, over time, healthy cells may replace these transformed cells or they may continue growing abnormally and become cancerous. The presence of transitional epithelial cells is normal. Treatment for ureteral cancer typically involves surgery. For viral UTIs, doctors may prescribe medication called antivirals. Your provider will let you know how much pee they need in the container for the test. Last reviewed May 2019. Or, if a large number of renal epithelial cells are discovered in urinalysis, then it could indicate a viral infection or problem with your kidneys.3. A urine cytology test screens your urine for precancer or cancer cells. Since your cytology analysis said that negative of HG urothelial carcinoma, the cytopathologist could not find even one cell which was HG (Suspicious for HG) or any cell looks abnormal (Atypical), so almost 100%, no cancer. Squamous epithelial cells are found in your urinary tract and are described as flat skin cells with an irregular outline. Urinalysis: A Comprehensive Review | AAFP ASCs in urine may precede a de novo histologic diagnosis of malignancy or be the first sign of a recurrence in the lower urinary tract, or the gynecologic tract (in women). Urine Cytology All Rights Reserved. The presence of a large number of epithelial cells in a urinalysis test may indicate a bacterial infection, however, having many squamous epithelial cells (SECs) in urine usually indicates that the urine sample was contaminated. Squamous cell carcinoma of the urinary bladder is a malignant neoplasm derived from bladder urothelium with pure squamous phenotype. Crystals may be seen in the urinary sediment of healthy patients (Figure 4). Etiologies include diabetes mellitus, Cushings syndrome, liver and pancreatic disease, and Fanconis syndrome. Cancer of the ureter (ureteral cancer) is an abnormal growth of cells on the inside lining of the tubes (ureters) that connect your kidneys to your bladder. Benign squamous cells Squamous Metaplasia: Causes, Symptoms and Treatments A moderate amount of squamous epithelial cells in the urine is not necessarily a cause for concern. Mayo Clinic does not endorse companies or products. Experiencing a burning sensation when you pee. Squamous epithelial cells are a type of flat cell found throughout the body, including in the mouth, on the lips, and on the cervix.